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Lipophilicity
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Keyword
keyword
Lipophilicity
RIS
0.001
(Research Intensity Score)
Papers
199
Top papers
Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design
2021 · 689 citations
Fluorine in the Pharmaceutical Industry: FDA‐Approved Fluorine‐Containing Drugs in 2024
2025 · 91 citations
Biological evaluations and biomolecular interactions along with computational insights of arylidene isatin hydrazones synthesized using nanocatalyst
2025 · 59 citations
Fluorinated Cycloalkyl Building Blocks for Drug Discovery
2022 · 102 citations
Flavonoids, Chalcones, and Their Fluorinated Derivatives—Recent Advances in Synthesis and Potential Medical Applications
2025 · 20 citations
Translational imaging of the fibroblast activation protein (FAP) using the new ligand [68Ga]Ga-OncoFAP-DOTAGA
2021 · 103 citations
Effect of gem ‐Difluorination on the Key Physicochemical Properties Relevant to Medicinal Chemistry: The Case of Functionalized Cycloalkanes
2022 · 88 citations
Structure–Activity Relationships and Biological Insights into PSMA-617 and Its Derivatives with Modified Lipophilic Linker Regions
2025 · 16 citations
A Comprehensive Review of the Biological Activities of Medicinal Metal Complexes Synthesized From Quinoline Scaffolds
2025 · 15 citations
Newest papers
Which halogen to choose? Comparing the effects of chlorine and fluorine as bioisosteric substituents in drug design
2026 · 6 citations
Sugar Amino Acid Linkers for the Design of [ 18 F]SiFA‐PSMA Radioligands
2026
Asymmetric organotellurium hard-soft donor schiff base ligand and its Cu(II)/Ni(II) complexes: DNA intercalation, anti-inflammatory and antimicrobial activity
2026 · 1 citations
Rational design, synthesis, and antimicrobial evaluation of novel 1,2,3-triazole hybrids: structure–activity relationships, molecular docking, and DFT studies
2026
Azomethines with Long Alkyl Chains: Synthesis, Characterization, Biological Properties and Computational Lipophilicity Assessment
2026 · 2 citations
2‐CF 2 H(D)‐Imidazolium Salts: A Reagent Platform for Bis(Deuterio)Difluoromethylation of Alkenes Under Copper/Photoredox Dual Catalysis
2026
Computational Design of Novel CB2 Partial Agonists: Mitigating hERG Toxicity and Stabilizing the Trp258 Microswitch via MPO and Molecular Dynamics
2026
Liposomal Formulations Containing Amino Acid Menthol Ester Naproxenate: Physicochemical Characterization and Transdermal Delivery Potential
2026
TrifluoromethylthioEngineering Enables a BalancedElectrostatic Potential for Organic Solar Cells with over 20% Efficiencyand Low Energy Loss
2026
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