Electrochemiluminescence Sensors and Nanomaterials for Ultrasensitive Bioassays
This community develops electrochemical light-emitting systems to detect biological molecules, toxins, and disease markers with extreme sensitivity.
The work centers on engineering electrochemiluminescent emitters and co-reactants to amplify signals for biosensing. Recurring materials include metal-organic frameworks, covalent organic frameworks, carbon nitrides, and noble metal nanoparticles such as gold and silver. Key methods involve energy transfer mechanisms, signal amplification strategies, and the use of nanozymes to enhance reaction rates. Applications are dominated by immunosensors and aptasensors for detecting specific proteins, DNA, and small molecules like hydrogen peroxide and aflatoxins. The research frequently explores ratiometric sensing and single-molecule detection capabilities to improve accuracy and lower detection limits.
The largest share of the community's output is found in ruthenium research, accounting for 1.2% of all ruthenium studies, with 880 papers in this group. Gold research contributes 514 papers, representing 0.3% of that element's total output, while carbon research includes 758 papers, or 0.1% of its total.
The community comprises 5,899 papers, published primarily in Analytical Chemistry, Biosensors and Bioelectronics, and Analytica Chimica Acta.
Recent work continues to focus on enhancing sensitivity for specific biomarkers, such as detecting hydrogen peroxide from cancer cells, cardiac troponin I, and tumor markers on living cell surfaces. Newer studies also explore wearable devices for sweat metabolite detection and the use of covalent organic frameworks for microRNA analysis, maintaining the core emphasis on ultrasensitive electrochemiluminescent detection.