Research community previously filed under “Catalysis”

Deep Eutectic Solvents for Green Extraction, Biomass Pretreatment, and Sustainable Separation

Mostly in the field Hydrometallurgy, Metal Recovery, and Sustainable Resource Processing (52% of its papers), one of 4 communities there

Papers 5,905
Elements —
Keywords & sectors 5
Leading venue Journal of Molecular Liquids

Deep Eutectic Solvents for Green Extraction, Biomass Pretreatment, and Sustainable Separation

This research community develops and applies deep eutectic solvents (DES) and natural deep eutectic solvents (NaDES) as green, recyclable media for extracting bioactive compounds, pretreating lignocellulosic biomass, and performing chemical separations.

The work centers on designing solvent mixtures, frequently using choline chloride paired with acids like lactic acid or ethylene glycol, to replace conventional organic solvents. Key applications include the extraction of phenolic compounds, antioxidants, and polysaccharides from plant materials and food by-products, as well as the pretreatment of lignocellulosic biomass to enhance enzymatic hydrolysis for bioethanol production. Methods span molecular dynamics simulations to optimize solvent structure, liquid-liquid microextraction for analytical chemistry, and extractive distillation for industrial separation. The emphasis is on sustainability, with a focus on green synthesis, solvent recyclability, and the reduction of hazardous waste in chemical processing.

The community is most heavily represented in research tracked for chlorine, accounting for 0.7% of all chlorine-related papers, followed by bromine at 0.3%. It also contributes to research on hydrogen, nitrogen, and carbon, each representing 0.1% of their respective element research.

There are 5,905 papers in this community, with the highest publication volumes in the Journal of Molecular Liquids, Separation and Purification Technology, and Food Chemistry.

Recent work continues to focus on optimizing DES for biomass pretreatment to improve bioethanol yields, developing sustainability assessment frameworks for solvent selection, and applying these solvents to the extraction of specific polysaccharides and polyphenols from agricultural residues.

Recurring themes in the literature

Phrases that recur across this community's paper titles -- a quick map of its sub-topics, drawn straight from the titles themselves.

  • deep eutectic 2330
  • eutectic solvents 1293
  • eutectic solvent 918
  • choline chloride 411
  • natural deep 218
  • ionic liquids 127
  • choline chloride-based 120
  • chloride-based deep 108
  • ionic liquid 93
  • ethylene glycol 85
  • liquid liquid 83
  • carbon dioxide 81
  • hydrophobic deep 80
  • chloride deep 72
  • acid deep 65
  • phenolic compounds 65
  • eutectic solvent-based 64
  • molecular dynamics 61
  • hydrogen bond 57
  • solvent pretreatment 56
  • green synthesis 56
  • liquid-liquid microextraction 52
  • liquid microextraction 52
  • chloride urea 50

Papers behind this description

Most cited
Nature Methods · 2021 · 1673 citations
Journal of environmental chemical engineering · 2025 · 131 citations
Pharmaceuticals · 2024 · 253 citations
Annual Review of Chemical and Biomolecular Engineering · 2023 · 382 citations
Nature Sustainability · 2024 · 226 citations
Newest
Biomass and Bioenergy · 2025 · 25 citations
Polysaccharides · 2025 · 23 citations
Renewable and Sustainable Energy Reviews · 2026 · 19 citations
Foods · 2025 · 17 citations
Fuel · 2025 · 18 citations

A sample from the 18 papers behind this description. Create a free account to see them all.