Research community previously filed under “Biomedical Engineering”

Photon-Counting and Dual-Energy CT Imaging and Spectral Analysis

Papers 14,866
Elements —
Keywords & sectors —
Leading venue Journal of the Optical Society of America

Photon-Counting and Dual-Energy CT Imaging and Spectral Analysis

This community develops and evaluates advanced X-ray imaging technologies, specifically photon-counting detectors and dual-energy systems, to improve diagnostic accuracy and reduce radiation exposure in clinical settings.

The research focuses heavily on the technical implementation of photon-counting computed tomography (PCCT) and dual-energy CT, analyzing their impact on image quality, radiation dose, and spectral data acquisition. Recurring themes include the use of deep learning for image reconstruction, the quantification of iodine concentration for contrast enhancement, and the application of virtual monoenergetic imaging. While the primary focus is on oncological applications—such as lung cancer, squamous cell carcinoma, and lymph node evaluation—the community also includes a distinct strand of work on calcium pyrophosphate deposition disease, utilizing spectral imaging to differentiate crystal types. The work bridges detector physics, algorithmic reconstruction, and clinical diagnostic performance.

The largest share of the community's output is found in selenium research, accounting for 2.6% of all selenium research, and 1,408 papers here. Iodine research also features prominently, with 1.6% of its research appearing in this group, comprising 1,314 papers.

The community comprises 14,866 papers, published most frequently in the Journal of the Optical Society of America, Medical Physics, and Physics in Medicine and Biology.

Recent work continues to compare the spectral performance of dual-energy and photon-counting scanners, including studies on reducing contrast media dosage for pulmonary embolism and using iodine maps to predict microsatellite instability in colorectal cancer.

Recurring themes in the literature

Phrases that recur across this community's paper titles -- a quick map of its sub-topics, drawn straight from the titles themselves.

  • computed tomography 691
  • calcium pyrophosphate 209
  • photon counting 198
  • photon-counting detector 170
  • image quality 160
  • dual-energy computed 154
  • deep learning 107
  • deposition disease 106
  • pyrophosphate deposition 101
  • dual energy 97
  • radiation dose 86
  • dual-layer spectral 74
  • x-ray imaging 70
  • extracellular volume 68
  • cell carcinoma 63
  • bone marrow 60
  • photon-counting computed 60
  • spectral detector 60
  • counting detector 60
  • magnetic resonance 59
  • virtual monoenergetic 58
  • detector computed 58
  • case report 56
  • image reconstruction 56

Papers behind this description

Most cited
Radiology · 2023 · 415 citations
Diagnostic and Interventional Imaging · 2025 · 136 citations
Nature Reviews Methods Primers · 2021 · 1087 citations
Diagnostic and Interventional Imaging · 2023 · 291 citations
Radiology · 2021 · 582 citations
Newest
Signal Transduction and Targeted Therapy · 2025 · 19 citations
Cement and Concrete Research · 2025 · 13 citations
Diagnostic and Interventional Imaging · 2025 · 8 citations
European Journal of Radiology · 2025 · 7 citations
Oral and Maxillofacial Surgery · 2025 · 7 citations

A sample from the 17 papers behind this description. Create a free account to see them all.