Oxidative Stress, Antioxidants, and Sperm Quality in Human and Domestic Animals
This community investigates how reactive oxygen species and oxidative stress affect sperm function and male fertility, and how antioxidant interventions or environmental exposures influence these outcomes in both human and animal models.
The research focuses heavily on the mechanisms of oxidative stress in sperm, including DNA fragmentation, motility loss, and mitochondrial dysfunction. A significant portion of the work examines the protective effects of antioxidant supplementation, such as vitamins C and E, and the impact of environmental factors like electromagnetic fields and zinc oxide nanoparticles on seminal plasma. The community also addresses practical applications in reproductive medicine, including cryopreservation techniques for human and bovine semen, and the role of extracellular vesicles in sperm function. Studies frequently employ systematic reviews and meta-analyses to synthesize data on male infertility parameters, while others explore the intersection of chronic endometritis and male reproductive health.
The largest share of the community's output is found in oxygen research, accounting for 0.2% of all oxygen-related papers, followed by selenium at 0.2% and zinc at 0.1%. Oxygen also contributes the highest number of papers to this group, with 917 entries.
The community comprises 3,505 papers, with the most frequent venues being Fertility and Sterility, Theriogenology, and Andrologia.
Recent work continues to explore the molecular mechanisms of reactive oxygen species in male reproductive health, including the role of extracellular vesicles in sperm and the impact of antioxidant strategies on asthenozoospermia.