Selenium Nanoparticles, Biofortification, and Selenoprotein Biology
This community investigates the chemistry, synthesis, and biological function of selenium, focusing on its role as an antioxidant, its delivery via nanoparticles and food biofortification, and its impact on human and animal health.
The research centers on the synthesis and characterization of selenium nanoparticles, often using green synthesis methods, and their application as antioxidant agents against oxidative stress. A significant portion of the work examines selenium supplementation, dietary intake, and biofortification of crops to improve nutritional status. The community also studies the molecular mechanisms of selenoproteins, particularly glutathione peroxidase, and their regulation in conditions such as cancer, diabetes, and neuroinflammation. Analytical techniques like mass spectrometry and vapor generation are frequently used to measure selenium levels in serum, tissues, and food products. The work frequently explores the interplay between selenium, zinc, and the gut microbiota, as well as the effects of selenium on gene expression and cellular redox balance.
The largest share of the community's output is found in selenium research, accounting for 46.0% of all selenium research and 22,570 papers within this group. Tellurium and arsenic research also appear, representing 2.8% and 1.0% of their respective element research, with 982 and 717 papers here.
The community comprises 32,052 papers, published primarily in Biological Trace Element Research, Analytica Chimica Acta, and Analytical Chemistry.
Recent work continues to focus on the synthesis of selenium nanoparticles for biomedical applications, including their role in mitigating oxidative stress and neuroinflammation. Studies also explore selenium's function in metabolic disorders, such as obesity and non-alcoholic fatty liver disease, and its interaction with other trace elements like silicon and cobalt in plant stress tolerance.