High-Resolution Electron Microscopy and Structural Imaging of Biological Systems
This community develops and applies advanced electron microscopy techniques to visualize the detailed architecture of cells, tissues, and macromolecules.
The research focuses on high-resolution imaging methods, including transmission electron microscopy, scanning electron microscopy, atomic force microscopy, and electron tomography. These techniques are used to examine the ultrastructure of biological samples, such as the endothelial glycocalyx, plasma membranes, and the skin barrier. The work also encompasses the structural characterization of proteins, viruses, and stem cells, often employing correlative light and electron microscopy to link functional context with high-resolution detail.
The largest share of the community's output is found in osmium research, accounting for 8.2% of all osmium research, and 883 papers here. Gold and silver also appear frequently, representing 1.1% and 0.9% of their respective element research, with 2,020 and 1,507 papers in this group.
The community comprises 22,390 papers, publishing primarily in Stain Technology, Journal of Histochemistry & Cytochemistry, and Brain Research.
Recent work includes the development of spontaneously blinking dyes for super-resolution microscopy and the use of soft X-ray tomography for correlative cryogenic biological imaging.