Oxidative Stress, Sperm Quality, and Male Infertility
This research community investigates how reactive oxygen species and oxidative stress affect sperm function, motility, and DNA integrity, with a focus on diagnosing male infertility and developing antioxidant strategies to preserve reproductive health in humans and domestic animals.
The work centers on measuring seminal plasma composition, sperm morphology, and DNA fragmentation using flow cytometry and other analytical methods. A major strand examines the protective effects of antioxidants on sperm quality during storage and cryopreservation. The community also studies the impact of environmental exposures, such as radiofrequency electromagnetic fields, on male reproductive parameters. While human clinical cases dominate, significant attention is given to boar, bovine, and poultry sperm, reflecting the dual importance of this research for human medicine and livestock breeding efficiency.
The community is most heavily represented in research tracked for Oxygen, accounting for 818 papers, followed by Iodine with 233 papers and Zinc with 188 papers. These elements appear in titles primarily as components of reactive species, antioxidants, or essential nutrients studied in the context of sperm health.
The community comprises 3,779 papers, with the highest publication volume in Andrologia, Fertility and Sterility, and Cytometry.
Recent work continues to focus on the molecular mechanisms of oxidative stress in asthenozoospermia and the development of antioxidant strategies, including the use of postbiotics and herbal supplements in semen extenders for cryopreservation.