Toxicology of Aluminum and Beryllium in Neurological and Pulmonary Systems
This community investigates the biological effects of aluminum and beryllium exposure, focusing on mechanisms of neurotoxicity, oxidative stress, and lung disease in animal models and human patients.
The research centers on aluminum chloride-induced Alzheimer’s disease models in Wistar rats, examining cognitive impairment and signaling pathways. A significant portion of the work addresses chronic beryllium disease, sarcoidosis, and interstitial lung fibrosis, often using rat models to assess oxidative stress and cellular toxicity. The community also explores aluminum adjuvants in vaccines, the presence of aluminum in drinking water, and the development of fluorescent probes for detecting these metals. Methods include in vivo exposure studies, pathological assessment of lung and brain tissue, and chemical analysis of metal interactions in biological systems.
The largest share of the community's output is found in beryllium research, representing 8.8% of all tracked beryllium papers, with 2,408 papers in this group. Aluminium research contributes 227 papers, accounting for 0.7% of that element's tracked literature.
The community comprises 12,809 papers, publishing most frequently in the Journal of the American Chemical Society, The Journal of Physical Chemistry, and Journal of Solution Chemistry.
Recent work includes a comprehensive narrative review on aluminum toxicity, studies on reducing residual aluminum in drinking water treatment, and research into the separation and purification of beryllium from minerals.