Superparamagnetic Iron Oxide Nanoparticles for Cancer Therapy and MRI
This community develops magnetic iron oxide nanoparticles for targeted cancer treatment, magnetic resonance imaging, and drug delivery.
The work centers on the synthesis and surface functionalization of superparamagnetic iron oxide (Fe3O4) and ferrite nanoparticles. These materials are engineered for specific biomedical roles, including magnetic hyperthermia to heat cancer cells, acting as contrast agents for MRI, and serving as carriers for targeted drug delivery. Research frequently explores core-shell structures, green synthesis methods, and the interaction of these particles with cancer cells and stem cells. The recurring focus is on optimizing magnetic properties for imaging and therapy while ensuring biocompatibility.
The largest share of the community's output is found in iron research, accounting for 2.7% of all iron research, with 10,135 papers here. Cobalt research also features prominently, representing 0.8% of that element's research with 1,039 papers.
The community comprises 16,490 papers, publishing most frequently in the Journal of Magnetism and Magnetic Materials, International Journal of Nanomedicine, and Nanoscale.
Recent work continues to focus on the clinical translation of superparamagnetic iron oxide nanoparticles, with studies addressing toxicity assessment, biosynthesis from biological sources, and their application in precision cancer theranostics.