Research community previously filed under “Biomedical Engineering”

Photon-Counting and Dual-Energy Computed Tomography for Clinical Imaging

Papers 10,945
Elements —
Keywords & sectors 5
Leading venue Journal of the Optical Society of America

Photon-Counting and Dual-Energy Computed Tomography for Clinical Imaging

This community develops detector technologies and reconstruction algorithms for X-ray computed tomography, enabling quantitative tissue characterization and improved image quality for diagnostic and interventional applications.

The research focuses on photon-counting detectors and dual-energy spectral acquisition, with a strong emphasis on iodine quantification and contrast media optimization. Recurring themes include image reconstruction techniques, radiation dose reduction, and the application of these imaging modalities to oncology, specifically lung, gastric, and colorectal cancers, as well as coronary angiography. The work bridges detector physics, such as Monte Carlo simulations and phantom studies, with clinical evaluation of image quality and quantitative parameters for detecting lymph node metastasis and assessing tumor response.

The community is most prominent in iodine research, accounting for 1.6% of all iodine-related papers, and in tellurium research, where it represents 1.0% of the element's tracked literature. It also holds a 0.5% share of gadolinium research, reflecting the use of these contrast agents in the imaging protocols.

The community comprises 10,945 papers, published primarily in the Journal of the Optical Society of America, Medical Physics, and Physics in Medicine and Biology.

Recent work continues to explore the clinical utility of photon-counting CT, with studies comparing spectral performance against dual-energy systems, assessing ultra-high spatial resolution in cardiothoracic imaging, and applying iodine maps for predicting molecular markers in colorectal cancer.

Recurring themes in the literature

Phrases that recur across this community's paper titles -- a quick map of its sub-topics, drawn straight from the titles themselves.

  • computed tomography 890
  • photon counting 270
  • image quality 235
  • dual-energy computed 215
  • photon-counting detector 190
  • dual energy 147
  • radiation dose 121
  • deep learning 121
  • dual-layer spectral 97
  • x-ray imaging 90
  • spectral computed 84
  • spectral detector 83
  • cell carcinoma 83
  • lymph node 80
  • virtual monoenergetic 79
  • detector computed 78
  • counting detector 75
  • iodine concentration 75
  • lung cancer 74
  • contrast media 69
  • photon-counting computed 66
  • iodine quantification 64
  • monte carlo 62
  • image reconstruction 61

Papers behind this description

Most cited
Radiology · 2023 · 415 citations
Diagnostic and Interventional Imaging · 2025 · 136 citations
Diagnostic and Interventional Imaging · 2023 · 291 citations
Radiology · 2021 · 582 citations
Radiology · 2023 · 172 citations
Newest
Quantitative Imaging in Medicine and Surgery · 2025 · 11 citations
European Radiology · 2025 · 9 citations
European Radiology Experimental · 2026 · 8 citations
Diagnostic and Interventional Imaging · 2025 · 8 citations
European Journal of Radiology · 2025 · 7 citations

A sample from the 18 papers behind this description. Create a free account to see them all.