Research community previously filed under “Cellular and Molecular Neuroscience”

Implantable Neural Interfaces and Electrode Materials for Brain and Spinal Cord Stimulation

Papers 6,836
Elements —
Keywords & sectors 2
Leading venue Journal of Neural Engineering

Implantable Neural Interfaces and Electrode Materials for Brain and Spinal Cord Stimulation

This community develops the electronic hardware and electrode materials used to record signals from, and deliver electrical stimulation to, the brain and spinal cord. The work focuses on creating durable, biocompatible interfaces that can interact with neural tissue for therapeutic and diagnostic purposes.

The research centers on the engineering of microelectrode arrays, flexible thin films, and conductive polymers such as PEDOT:PSS and iridium oxide. These materials are designed to improve the stability and signal quality of neural recording and stimulation leads. Applications include deep brain stimulation for Parkinson's disease, spinal cord stimulation for pain management, and cochlear implants. The work also addresses the fabrication of field-effect transistors and carbon fiber electrodes to enhance the sensitivity of neural interfaces. Recent efforts emphasize the integration of these components into wireless, battery-less implants and scalable manufacturing processes for high-density cortical arrays.

The community is most heavily concentrated in research tracked for Iridium, accounting for 2.9% of all Iridium-related papers, with 1,073 papers in this group. It also contributes to research on Lead, representing 0.3% of that element's tracked literature with 309 papers.

The community comprises 6,836 papers, with the highest publication volume in the Journal of Neural Engineering, bioRxiv, and Sensors and Actuators B Chemical.

Recent work includes the development of ultra-high-density Neuropixels probes for neuronal recording, minimally invasive implantation of scalable high-density cortical microelectrode arrays, and the use of PEDOT:PSS conducting eutectogels for enhanced electrical recording and stimulation in implantable neural interfaces.

Recurring themes in the literature

Phrases that recur across this community's paper titles -- a quick map of its sub-topics, drawn straight from the titles themselves.

  • deep brain 139
  • brain stimulation 123
  • spinal cord 83
  • iridium oxide 70
  • microelectrode arrays 51
  • electrical stimulation 46
  • cord stimulation 35
  • neural interfaces 35
  • field-effect transistor 33
  • neural interface 33
  • stimulation lead 32
  • neural recording 30
  • microelectrode array 30
  • magnetic resonance 30
  • carbon fiber 29
  • lead placement 27
  • cochlear implant 27
  • thin films 26
  • resonance imaging 26
  • field transistor 25
  • cord stimulator 25
  • thin film 25
  • parkinson disease 25
  • case report 24

Papers behind this description

Most cited
Nature Medicine · 2022 · 453 citations
Nature Biotechnology · 2024 · 136 citations
NeuroImage · 2023 · 230 citations
Nature Nanotechnology · 2024 · 135 citations
Nature Biotechnology · 2023 · 146 citations
Newest
Neuron · 2025 · 24 citations
Sensors · 2025 · 19 citations
Nature Biomedical Engineering · 2025 · 13 citations
Journal of Materials Chemistry C · 2025 · 8 citations
Advanced Healthcare Materials · 2025 · 8 citations

A sample from the 13 papers behind this description. Create a free account to see them all.