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Gene knockdown
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Keyword
keyword
Gene knockdown
RIS
0.004
(Research Intensity Score)
Papers
443
Top papers
ABCF1-K430-Lactylation promotes HCC malignant progression via transcriptional activation of HIF1 signaling pathway
2025 · 82 citations
Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer
2021 · 300 citations
Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis
2025 · 30 citations
The STAT1/HMGB1/NF-κB pathway in chronic inflammation and kidney injury after cisplatin exposure
2023 · 99 citations
Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury
2019 · 570 citations
circCUL2 regulates gastric cancer malignant transformation and cisplatin resistance by modulating autophagy activation via miR-142-3p/ROCK2
2020 · 239 citations
ALKBH5 Inhibited Cell Proliferation and Sensitized Bladder Cancer Cells to Cisplatin by m6A-CK2α-Mediated Glycolysis
2020 · 240 citations
EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance
2024 · 43 citations
Adrenomedullin induces cisplatin chemoresistance in ovarian cancer through reprogramming of glucose metabolism
2023 · 54 citations
Newest papers
Lactylation enhances YTHDF3 stability to promote cisplatin resistance via m6A-dependent KDM6B decay in bladder cancer
2026 · 6 citations
An H4K12la/CEBPB-AKR1C2 signaling axis modulates the mTOR pathway to regulate cisplatin resistance in lung cancer
2026 · 6 citations
ALKBH5 enhances cadmium-induced stemness enrichment and proliferation of colon cancer cells via m6A-dependent regulation of AXIN2 and activation of Wnt/β-catenin signaling
2026 · 4 citations
NOX4/Keap1/Nrf2/ROS signaling drives ferroptosis in trimethyltin chloride-induced cardiac developmental malformations
2026 · 4 citations
NAT10 promotes cisplatin resistance and immune escape by increasing the expression of DUSP1 and PD-L1 in gastric cancer
2026 · 2 citations
TMEM11 promotes cisplatin resistance by inhibiting BNIP3-mediated mitophagy in bladder cancer
2026 · 3 citations
UBC9-mediated p53 SUMOylation drives tubular senescence and exacerbates acute kidney injury in mice
2026 · 3 citations
The copper transporter protein SLC31A1-mediated copper metabolism imbalance drives cuproptosis through the SIRT1/HMGB1 pathway in heart failure
2026 · 2 citations
Single-cell insights into cisplatin resistance mechanisms in bladder cancer tumor microenvironment
2026 · 2 citations
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