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Germline mutation
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Keyword
keyword
Germline mutation
RIS
0.001
(Research Intensity Score)
Papers
69
Top papers
Maintenance Olaparib for Germline BRCA -Mutated Metastatic Pancreatic Cancer
2019 · 2231 citations
Advances in Precision Oncology: From Molecular Profiling to Regulatory-Approved Targeted Therapies
2025 · 13 citations
Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation
2019 · 208 citations
Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency
2025 · 10 citations
Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer
2020 · 157 citations
A case of long-term survival in unresectable pancreatic cancer with BRCA germline mutation treated with platinum-based chemotherapy
2026 · 1 citations
Breast Cancer: Epidemiology, Molecular Classification, Diagnostics and Evolving Treatment Paradigms
2026 · 1 citations
Real-World Germline Testing Patterns and Clinical Implications of HRR-Associated Germline Variants in Pancreatic Ductal Adenocarcinoma
2026
Randomized phase 2 trial of a PARP inhibitor TSL-1502 in germline BRCA-mutated, HER2-negative locally advanced/metastatic breast cancer
2026
Newest papers
A case of long-term survival in unresectable pancreatic cancer with BRCA germline mutation treated with platinum-based chemotherapy
2026 · 1 citations
Breast Cancer: Epidemiology, Molecular Classification, Diagnostics and Evolving Treatment Paradigms
2026 · 1 citations
Real-World Germline Testing Patterns and Clinical Implications of HRR-Associated Germline Variants in Pancreatic Ductal Adenocarcinoma
2026
Randomized phase 2 trial of a PARP inhibitor TSL-1502 in germline BRCA-mutated, HER2-negative locally advanced/metastatic breast cancer
2026
Explainable machine learning relates histological to genomic pathology
2026
Concurrent Germline RB1 & Mosaic TP53 in a Child With Multiple Childhood Cancers
2026
Characterization of putative germline pathogenic variants in 27 candidate cancer-predisposing genes in 813 cats using a feline-specific multiplex targeted sequencing
2026
Mainstream and fast-track genetic testing in pancreatic cancer patients and its impact on treatment: our experience in a tertiary hospital in Spain
2026
Beyond Fat: Reframing MASLD Through Genetics, Clonal Biology, and Precision Hepatology
2026
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