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Histone deacetylase
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Keyword
keyword
Histone deacetylase
RIS
0.001
(Research Intensity Score)
Papers
79
Top papers
HDAC2‐Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple‐Negative Breast Cancer
2025 · 43 citations
Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6
2023 · 48 citations
Next-Generation HDAC Inhibitors: Advancing Zinc-Binding Group Design for Enhanced Cancer Therapy
2025 · 10 citations
Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding Groups
2025 · 15 citations
The Zinc-Binding Group Effect: Lessons from Non-Hydroxamic Acid Vorinostat Analogs
2023 · 45 citations
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models
2020 · 211 citations
Exploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers DS-103 as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing Properties
2025 · 13 citations
The brain neurovascular epigenome and its association with dementia
2025 · 8 citations
Asparagine transporter supports macrophage inflammation via histone phosphorylation
2025 · 10 citations
Newest papers
Epigenetic Metal‐Organic Framework Nanoagonist Overcomes Triple Defenses to Enable Effective Chemo‐Metalloimmunotherapy in Platinum‐Resistant Ovarian Cancer
2026 · 4 citations
Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer
2026 · 3 citations
Molecular Effect of Tobacco on Genetic, Epigenetic, and Metabolic Pathways During Cancer Progression
2026 · 3 citations
An acetylation-dependent switch underlies host disease tolerance during streptococcal infection
2026 · 2 citations
Targeting HDAC and proteostasis to eradicate quiescent cancer cells
2026
Role of Sodium Phenylbutyrate and Suramin in the Prevention of Ulcerative Colitis Induced by Dextran Sulfate Sodium
2026
Quinazolinone–hydroxamate derivatives as potential HDAC8 inhibitors: An integrated docking, ADME, DFT, and molecular dynamics study
2026
Highlighted Research Articles
2026
HDAC6 is a biomarker of leukaemic dissemination and relapse in B-ALL
2026
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