Liver Cancer and Biliary Tract Malignancy: Imaging, Interventional Therapy and Systemic Treatment
This community focuses on the diagnosis and management of hepatocellular carcinoma and cholangiocarcinoma, utilizing advanced imaging techniques, interventional radiology procedures, and systemic pharmacological therapies to treat liver malignancies.
The research centers on the clinical management of hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Recurring themes include the use of magnetic resonance imaging for diagnosis and staging, alongside interventional procedures such as transarterial chemoembolization and yttrium-90 radioembolization. A significant portion of the work addresses advanced biliary tract cancer, specifically evaluating combinations of chemotherapy agents like gemcitabine and cisplatin with immunotherapies. The community also investigates liver transplantation outcomes, portal vein involvement, and the application of deep learning algorithms in medical imaging. These studies predominantly consist of clinical trials, systematic reviews, and case reports detailing treatment protocols and patient outcomes for these specific liver malignancies.
The largest share of the community's output is found in yttrium research, accounting for 1.6% of all yttrium research, and 1,578 papers here. Gadolinium research also features prominently, representing 1.8% of that element's research with 1,146 papers. Platinum research contributes 982 papers, making up 0.7% of platinum research.
The community comprises 23,405 papers, with the highest publication volumes in the World Journal of Gastroenterology, Journal of Magnetic Resonance Imaging, and Frontiers in Oncology.
Recent work continues to focus on the status quo and unmet needs in cholangiocarcinoma, the diagnosis and treatment of hepatocellular carcinoma, and the quantification of liver fat in fatty liver disease using magnetic resonance imaging. Other recent studies examine bicarbonate-integrated transarterial chemoembolization, the comparison of yttrium-90 radioembolization with conventional chemoembolization, and the use of hepatic arterial infusion pump chemotherapy for unresectable intrahepatic cholangiocarcinoma.