Research community previously filed under “Health, Toxicology and Mutagenesis”

Heavy Metal Toxicology and Human Health Risk Assessment

Papers 24,708
Elements 5
Keywords & sectors 48
Leading venue Biological Trace Element Research

Heavy Metal Toxicology and Human Health Risk Assessment

This community investigates the biological effects of toxic metals, primarily cadmium, lead, and mercury, to quantify their impact on human physiology and environmental safety.

The research focuses on the mechanisms of oxidative stress and cellular damage caused by exposure to these elements. A significant portion of the work involves animal models, particularly Wistar rats, to study the physiological responses to cadmium and lead. The community also conducts extensive risk assessments to evaluate the health implications of metal contamination in drinking water, food sources, and the broader environment. Studies frequently examine the bioaccumulation of these metals in blood and tissues, analyzing the resulting toxicological profiles and potential links to chronic disease.

The largest share of the community's output is found in cadmium research, accounting for 18.4% of all cadmium research, and 9,164 papers here. Mercury research follows with a 10.7% share, and lead research with a 6.9% share.

The community comprises 24,708 papers, publishing most frequently in Biological Trace Element Research, Ecotoxicology and Environmental Safety, and Environmental Research.

Recent work continues to examine the specific mechanisms of lead and cadmium toxicity, including their effects on reproductive health and the disruption of intestinal barriers. Newer studies also explore the co-occurrence of heavy metals with microplastics in water systems and the use of computational modeling to predict groundwater pollution risks.

Recurring themes in the literature

Phrases that recur across this community's paper titles -- a quick map of its sub-topics, drawn straight from the titles themselves.

  • heavy metals 706
  • heavy metal 536
  • oxidative stress 526
  • cadmium exposure 524
  • risk assessment 338
  • lead cadmium 282
  • health risk 270
  • cadmium lead 219
  • cadmium toxicity 179
  • human health 154
  • exposure cadmium 135
  • cadmium chloride 134
  • wistar rats 134
  • lead poisoning 133
  • trace elements 129
  • cadmium induced 128
  • against cadmium-induced 126
  • health risks 125
  • lead exposure 125
  • blood lead 120
  • mercury exposure 112
  • metal exposure 111
  • assessment heavy 111
  • drinking water 100

Papers behind this description

Most cited
Chemico-Biological Interactions · 2022 · 1093 citations
Toxics · 2023 · 511 citations
Circulation Research · 2024 · 300 citations
Molecules · 2023 · 422 citations
Sustainability · 2025 · 195 citations
Chemistry and Ecology · 2024 · 325 citations
Environmental Chemistry and Ecotoxicology · 2023 · 486 citations
Toxics · 2025 · 127 citations
Toxics · 2024 · 202 citations
Heliyon · 2025 · 137 citations
Chemosphere · 2022 · 404 citations
Biomolecules · 2022 · 309 citations
Newest
Journal of Xenobiotics · 2025 · 66 citations
Toxics · 2025 · 26 citations
International Journal of Molecular Sciences · 2025 · 23 citations
Pollutants · 2025 · 21 citations
Discover Applied Sciences · 2025 · 19 citations
Discover Environment · 2025 · 18 citations