Nanozymes and Hydrogels for Wound Repair and Cancer Therapy
This community develops enzyme-mimicking nanomaterials and hydrogel-based delivery systems to treat chronic wounds, inflammatory diseases, and cancer.
The work centers on cerium oxide and other metal oxide nanoparticles designed to mimic peroxidase or catalase activity, regulating reactive oxygen species in biological tissues. These nanozymes are integrated into hydrogels, often combined with sodium alginate or metal-organic frameworks, to create wound dressings for diabetic ulcers and infected sites. A parallel strand applies these materials to cancer treatment, using photothermal, photodynamic, and chemodynamic therapies to modulate the tumor microenvironment and enhance immunotherapy. Colorimetric detection methods are also developed to screen for cancer biomarkers using these nanozymatic platforms.
The largest share of the community's output is found in cerium research, accounting for 5.6% of all cerium research, and 4,249 papers here. Oxygen research also contributes significantly, with 7,258 papers representing 1.4% of that element's research.
The community comprises 25,844 papers, publishing most frequently in Chemical Engineering Journal, ACS Nano, and Journal of Nanobiotechnology.
Recent work focuses on multifunctional hydrogels for diabetic foot ulcers, nanozymes for portable cancer screening, and light-activated therapies for antibiotic-resistant biofilm infections.