Calcium Phosphate and Carbonate Biomaterials for Bone and Dental Repair
This community develops mineral-based materials, including calcium phosphates and carbonates, to repair bone defects, regenerate tissue, and treat dental conditions.
The work centers on synthesizing and characterizing hydroxyapatite, bioactive glasses, and phosphate cements for use as bone grafts and scaffolds. A significant portion of the research focuses on microbially induced carbonate precipitation and the development of strontium- or magnesium-doped composites to enhance mechanical strength and biological activity. These materials are evaluated for their ability to support stem cell integration and facilitate tissue regeneration in orthopedic and dental applications. The research also includes the formulation of silver diamine fluoride treatments for dental caries and the design of drug delivery systems that release therapeutic agents directly to the site of injury.
The largest share of the community's output is found in calcium research, accounting for 27.4% of all calcium research, and 9,736 papers here. Strontium research also features prominently, representing 10.3% of that element's literature.
The community comprises 22,511 papers, with the highest publication volume in Ceramics International, Biomaterials, and Acta Biomaterialia.
Recent work continues to focus on 3D-printed scaffolds for bone defect repair, strontium-releasing biomaterials, and the development of bioactive glasses with enhanced antibacterial properties.
Papers behind this description
- Bone Regeneration: A Review of Current Treatment Strategies — Journal of Clinical Medicine, 2025 — doi:10.3390/jcm14061838
- Engineering Large‐Scale Self‐Mineralizing Bone Organoids with Bone Matrix‐Inspired Hydroxyapatite Hybrid Bioinks — Advanced Materials, 2024 — doi:10.1002/adma.202309875
- Application of Hydroxyapatite Composites in Bone Tissue Engineering: A Review — Journal of Functional Biomaterials, 2025 — doi:10.3390/jfb16040127
- Bone Tissue Engineering in the Treatment of Bone Defects — Pharmaceuticals, 2022 — doi:10.3390/ph15070879
- Microbial‑induced carbonate precipitation (MICP) technology: a review on the fundamentals and engineering applications — Environmental Earth Sciences, 2023 — doi:10.1007/s12665-023-10899-y
- Recent advances in 3D-printed polylactide and polycaprolactone-based biomaterials for tissue engineering applications — International Journal of Biological Macromolecules, 2022 — doi:10.1016/j.ijbiomac.2022.07.140
- Recent Advances in Hydroxyapatite-Based Biocomposites for Bone Tissue Regeneration in Orthopedics — International Journal of Molecular Sciences, 2022 — doi:10.3390/ijms23179721
- Vascular endothelial growth factor (VEGF) and endogenous calcium-capturing gelatin methacrylate hydrogels promote bone tissue regeneration — Biomaterials, 2025 — doi:10.1016/j.biomaterials.2025.123352
- Advances in strontium-releasing biomaterials for bone repair — Biomaterials, 2026 — doi:10.1016/j.biomaterials.2025.123718
- Enzyme‐Programmable DNA‐PEG Hydrogel Spatiotemporally Regulates Bone Regeneration Microenvironment — Advanced Materials, 2025 — doi:10.1002/adma.202514461
- Advances in 3D-Printed scaffolds for bone defect repair: material strategies and synergistic functional performance — Frontiers in Bioengineering and Biotechnology, 2025 — doi:10.3389/fbioe.2025.1707406
- Biocompatibility and dissolution experiments with molecular dynamics structural characterization of melt-derived Mg-substituted silicate bioactive potential glasses — Journal of Non-Crystalline Solids, 2025 — doi:10.1016/j.jnoncrysol.2025.123855