Research community previously filed under “Biomedical Engineering”

Calcium Phosphate and Titanium Biomaterials for Bone Regeneration and Implant Integration

Papers 50,063
Elements 5
Keywords & sectors 86
Leading venue Ceramics International

Calcium Phosphate and Titanium Biomaterials for Bone Regeneration and Implant Integration

This community develops inorganic and metallic materials designed to repair skeletal defects, support tissue growth, and improve the integration of orthopedic and dental implants.

The research centers on the synthesis and application of calcium phosphate ceramics, including hydroxyapatite and biphasic composites, often combined with bioactive glasses or phosphate cements. A major focus is the modification of titanium surfaces through coatings, porosity engineering, and alloy development to enhance osseointegration. These materials are frequently studied in the context of scaffolds for tissue engineering, drug delivery systems, and the treatment of bone defects. The work frequently involves evaluating osteogenic differentiation, antibacterial properties, and mechanical performance in vitro and in animal models to optimize the biological response of the implant or graft.

The largest share of this community's output is found in calcium research, representing 13.0% of all calcium research, with 14,615 papers in this group. It also constitutes a significant portion of phosphorus (7.1%) and titanium (6.2%) research.

The community comprises 50,063 papers, published primarily in Ceramics International, Biomaterials, and Acta Biomaterialia.

Recent work continues to focus on advanced scaffold fabrication, including 3D bioprinting and injectable cements, as well as the development of strontium-releasing biomaterials and hydrogel-based systems for bone repair and implant integration.

Recurring themes in the literature

Phrases that recur across this community's paper titles -- a quick map of its sub-topics, drawn straight from the titles themselves.

  • calcium phosphate 1478
  • bone regeneration 985
  • tissue engineering 878
  • bone tissue 744
  • bioactive glass 532
  • stem cells 364
  • finite element 362
  • titanium implants 338
  • mesenchymal stem 259
  • dental implants 235
  • biphasic calcium 232
  • tricalcium phosphate 230
  • scaffolds bone 214
  • drug delivery 212
  • tissue regeneration 212
  • bone defects 209
  • osteogenic differentiation 199
  • bone defect 193
  • titanium alloy 192
  • bone repair 191
  • bioactive glasses 188
  • phosphate cement 182
  • titanium surface 179
  • calcium phosphates 172

Papers behind this description

Most cited
Journal of Nanobiotechnology · 2025 · 148 citations
Journal of Clinical Medicine · 2025 · 130 citations
Military Medical Research · 2023 · 345 citations
Advanced Science · 2023 · 244 citations
International Journal of Molecular Sciences · 2024 · 173 citations
Newest
Stem Cell Research & Therapy · 2025 · 42 citations
Journal of Functional Biomaterials · 2025 · 43 citations
Biomaterials · 2025 · 32 citations
Biomaterials · 2026 · 27 citations
Advanced Materials · 2025 · 24 citations

A sample from the 11 papers behind this description. Create a free account to see them all.