Calcium Phosphate and Bioactive Glass Scaffolds for Bone Regeneration and Tissue Repair
This research community develops synthetic biomaterials, primarily calcium phosphates and bioactive glasses, to create scaffolds and cements that facilitate bone healing, tissue regeneration, and the delivery of therapeutic agents.
The work centers on the synthesis and characterization of hydroxyapatite, tricalcium phosphate, and biphasic calcium phosphate composites. These materials are engineered into porous scaffolds, hydrogels, and injectable cements, often combined with biopolymers like sodium alginate, chitosan, or silk fibroin. The primary applications are the repair of critical bone defects, the promotion of osteogenic differentiation in stem cells, and the management of bone infections. Researchers also investigate the mechanical properties and antibacterial activity of these composites, frequently incorporating strontium or zinc to enhance biological performance.
The community is most heavily concentrated in calcium research, representing 8.1% of all tracked calcium papers, and phosphorus research, accounting for 6.9% of that element’s output. It also constitutes 6.1% of strontium research. Calcium is both the largest share and the highest paper count within this group.
The community comprises 45,423 papers, with the highest publication volume in Ceramics International, Acta Biomaterialia, and Biomaterials.
Recent work focuses on immunomodulatory hydrogels for infected bone defects, strontium-releasing biomaterials for bone repair, and AI-driven design of biomaterials.