Nanozymes and Hydrogels for Wound Healing and Inflammatory Disease
This community develops enzyme-mimicking nanomaterials and hydrogel dressings to treat chronic wounds, manage oxidative stress, and detect biomarkers in inflammatory conditions.
The work centers on cerium oxide nanoparticles and other metal-oxide nanozymes that mimic peroxidase or catalase activity to scavenge reactive oxygen species. These materials are frequently integrated into hydrogels or metal-organic frameworks to create dressings for diabetic foot ulcers, infected wounds, and spinal cord injuries. A significant portion of the research focuses on colorimetric detection of hydrogen peroxide and other biomarkers, as well as antibacterial strategies for multidrug-resistant infections. The applications extend to treating rheumatoid arthritis and ulcerative colitis by modulating the local oxidative environment.
The largest share of the community's output is found in cerium research, accounting for 9.1% of all cerium research and 3,388 papers within this group. It also contributes 0.6% of platinum research and 0.5% of gold research.
The community comprises 12,671 papers, published most frequently in Chemical Engineering Journal, International Journal of Biological Macromolecules, and Journal of Nanobiotechnology.
Recent work continues to focus on hydrogel-based strategies for diabetic wound repair, oxygen-vacancy engineering in ceria nanozymes for sensing, and metal-organic frameworks for biomedical applications.