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Tyrosine kinase
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Keyword
keyword
Tyrosine kinase
RIS
0.001
(Research Intensity Score)
Papers
93
Top papers
Hepatocellular carcinoma: signaling pathways and therapeutic advances
2025 · 322 citations
Osimertinib with or without Chemotherapy in EGFR -Mutated Advanced NSCLC
2023 · 681 citations
Lung Cancer in Nonsmoking Individuals
2025 · 30 citations
Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer
2016 · 3369 citations
Osimertinib versus platinum–pemetrexed for patients with EGFR T790M advanced NSCLC and progression on a prior EGFR-tyrosine kinase inhibitor: AURA3 overall survival analysis
2020 · 278 citations
Phase II Dose-Randomized Study of Sunvozertinib in Platinum-Pretreated Non–Small Cell Lung Cancer With Epidermal Growth Factor Receptor Exon 20 Insertion Mutations (WU-KONG1B)
2025 · 17 citations
The role of microglia in multiple sclerosis: implications for treatment with Bruton’s tyrosine kinase inhibitors
2025 · 18 citations
The Role of Plant-Derived Natural Products as a Regulator of the Tyrosine Kinase Pathway in the Management of Lung Cancer
2025 · 10 citations
Promoting reactive oxygen species accumulation to overcome tyrosine kinase inhibitor resistance in cancer
2024 · 19 citations
Newest papers
A Gold-PROTAC Degrades the Oncogenic Tyrosine Kinase MERTK: Insights into the Degradome from a Steady-State System
2026 · 3 citations
Gastrointestinal Stromal Tumors: Molecular Mechanisms of Drug Resistance and Advances in Therapeutic Strategies
2026 · 2 citations
Dynamic phenotyping of radioiodine-refractory differentiated thyroid cancer: thyroglobulin trajectories, dual-modal imaging, and genotype-defined treatment resistance
2026
Editorial: EGFR-targeted therapy in lung cancer: unraveling molecular regulation, overcoming resistance, and advancing precision clinical practice
2026
Sitravatinib combined with osimertinib overcomes acquired osimertinib resistance in NSCLC by targeting AXL and the PI3K/AKT/GSK3β signaling pathway
2026
Targeting oncogenic FLT3 uncovers a ferroptosis vulnerability through selenocysteine recoding in acute myeloid leukaemia
2026
Structure-based scaffold hopping reveals strategies to overcome oncogenic KIT and PDGFRA mutation-driven drug-resistance in GIST
2026
Novel Functionalized Pyrrolopyridines to Target Brk
2026
Andamertinib: First Approval
2026
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