Research community previously filed under “Health, Toxicology and Mutagenesis”

Heavy Metal Toxicology and Human Health Risk Assessment

Part of the field Heavy Metal Contamination, Exposure, and Human Health Risk Assessment, one of 4 communities there

Papers 55,218
Elements 7
Keywords & sectors 64
Leading venue Biological Trace Element Research

Heavy Metal Toxicology and Human Health Risk Assessment

This community investigates the physiological effects of toxic metals, primarily lead and cadmium, on human and animal health, focusing on exposure pathways, oxidative stress mechanisms, and associated chronic diseases.

The research centers on quantifying exposure to lead and cadmium through blood levels, environmental samples, and dietary intake. Recurring themes include the assessment of oxidative stress, kidney disease, and cardiovascular impacts resulting from chronic exposure. Studies frequently employ animal models, particularly Wistar rats, to test protective agents against cadmium-induced toxicity. The work also encompasses risk assessment methodologies, trace element analysis, and the investigation of links between metal exposure and conditions such as autism spectrum disorder and reproductive health issues.

The largest share of the community's output is found in cadmium research, accounting for 13.5% of all cadmium research, and 21,435 papers here. Lead research follows with 8.5% of all lead research, and 17,913 papers here.

The community comprises 55,218 papers, publishing most frequently in Biological Trace Element Research, Environmental Research, and Ecotoxicology and Environmental Safety.

Recent work continues to examine the mechanisms of lead toxicity in living organisms and the health hazards of heavy metals in drinking water. Newer studies also address environmental lead risk in the 21st century and the immune-epigenetic effects of environmental pollutants, including transgenerational impacts.

Recurring themes in the literature

Phrases that recur across this community's paper titles -- a quick map of its sub-topics, drawn straight from the titles themselves.

  • heavy metals 1420
  • heavy metal 1005
  • oxidative stress 825
  • lead exposure 676
  • cadmium exposure 662
  • blood lead 497
  • trace elements 439
  • risk assessment 420
  • lead cadmium 381
  • lead levels 342
  • metal exposure 327
  • health risk 325
  • cadmium lead 269
  • wistar rats 250
  • lead poisoning 226
  • cadmium chloride 218
  • cadmium toxicity 208
  • toxic metals 204
  • trace element 188
  • cadmium induced 186
  • exposure cadmium 184
  • against cadmium-induced 184
  • toxic elements 174
  • human health 168

Papers behind this description

Most cited
Chemico-Biological Interactions · 2022 · 1122 citations
Heliyon · 2023 · 512 citations
Toxics · 2023 · 525 citations
Circulation Research · 2024 · 306 citations
Molecules · 2023 · 433 citations
Newest
Journal of Xenobiotics · 2025 · 67 citations
International Journal of Molecular Sciences · 2025 · 30 citations
Communications Earth & Environment · 2025 · 30 citations
Discover Applied Sciences · 2025 · 23 citations
Pollutants · 2025 · 23 citations

A sample from the 18 papers behind this description. Create a free account to see them all.