Transition-Metal Catalysis for Hydrogenation, Dehydrogenation, and Hydroformylation
This community develops catalysts based on transition metals to drive hydrogen transfer, hydrogenation, and hydroformylation reactions. The work focuses on creating efficient systems for converting alcohols, acids, and alkenes into valuable chemical intermediates, with a strong emphasis on asymmetric synthesis and the use of formic acid as a hydrogen source.
The research centers on the design of metal complexes, particularly those involving ruthenium, iridium, rhodium, cobalt, and manganese. Recurring methodologies include transfer hydrogenation, asymmetric hydrogenation, reductive amination, and dehydrogenative coupling. Key substrates and products involve formic acid, carbon dioxide, primary and secondary alcohols, and carbonyl compounds. The field frequently employs pincer ligands and metal-ligand cooperativity to achieve high selectivity and efficiency under mild conditions. Applications range from the synthesis of chiral pharmaceuticals to the production of hydrogen and the conversion of carbon dioxide into formic acid.
The largest share of the community's output is found in rhodium research, accounting for 23.6% of all rhodium research, and 2,420 papers here. Iridium research follows with a 19.2% share, and ruthenium research with an 11.0% share.
The community comprises 20,122 papers, published primarily in Organometallics, the Journal of the American Chemical Society, and the Journal of Organometallic Chemistry.
Recent work includes the development of iridium-catalyzed ionic hydrogenation of pyridines, cobalt-catalyzed hydrogenation of allenes, and the construction of zeolite-anchored rhodium sites for ethylene hydroformylation.